December 2021
This case series introduces a novel therapy combining platelet-rich plasma (PRP) with fat grafting to improve hair quality and density in patients with non-scarring alopecia.
Why this matters
This case series introduces a novel therapy combining platelet-rich plasma (PRP) with fat grafting to improve hair quality and density in patients with non-scarring alopecia. This work contributes to evidence-based plastic and reconstructive surgery — helping clinicians interpret outcomes, refine technique, and counsel patients with clearer data.
Author
Plastic and reconstructive surgery resident at Emory University (UCLA BS, USC MD) with an h-index of 21 and peer-reviewed work spanning aesthetic surgery, reconstruction, medical devices, and AI in medicine.
Abstract
This case series introduces a novel therapy combining platelet-rich plasma (PRP) with fat grafting to improve hair quality and density in patients with non-scarring alopecia. The treatment builds on the synergistic effects of PRP’s growth signaling and fat grafting’s angiogenic properties, enhancing scalp quality and hair restoration outcomes. Three cases are presented: a female patient with alopecia post-COVID-19 hospitalization and two males with androgenic alopecia. All patients showed improved hair density and quality, with visible growth starting at 4 weeks, peaking at 12 weeks, and sustained through 6 months to 1 year. This approach demonstrates promise over PRP alone but requires further clinical studies for validation.